Restraint stress enhances arterial thrombosisin vivo– role of the sympathetic nervous system

Restraint stress enhances arterial thrombosis in vivo--role of the sympathetic nervous system.

Stress is known to correlate with the incidence of acute myocardial infarction. However, the molecular mechanisms underlying this correlation are not known. This study was designed to assess the effect of experimental stress on arterial thrombus formation, the key event in acute myocardial infarction. Mice exposed to 20 h of restraint stress displayed an increased arterial prothrombotic potenti...

locus coeruleus lesion & cold stress: role of the central and peripheral sympathetic nervous system in rat’s late proestrous phase

objective: lc/na system is activator of hypothalamic–pituitar–adrenal (hpa) axis and cold stress triggers an equally robust increase in plasma na. increased lhrh content probably due to absence or decrease of ne release from the lc and positive feedback action of e2 on lh secretion show that in late proestrous phase na, lh and e2 have a strong link. this study was conducted to evaluate the effe...

Role of the sympathetic nervous system in supporting cardiac function in essential arterial hypertension.

Treatment of hypertension with sympathetic blocking agents may convert latent cardiac failure into overt failure. Detection of early cardiac insufficiency is desirable. Thirty patients with essential hypertension without history or symptoms of circulatory decompensation were investigated. According to the changes induced by digitalis on the left ventricular mean rates of systolic ejection and i...

Pathophysiology of Resistant Hypertension: The Role of Sympathetic Nervous System

Resistant hypertension (RH) is a powerful risk factor for cardiovascular morbidity and mortality. Among the characteristics of patients with RH, obesity, obstructive sleep apnea, and aldosterone excess are covering a great area of the mosaic of RH phenotype. Increased sympathetic nervous system (SNS) activity is present in all these underlying conditions, supporting its crucial role in the path...

Autonomic Nervous System Influences: The Role of the Sympathetic Nervous System in Female Sexual Arousal